High concern

Red 40

Allura Red AC · FD&C Red No. 40 · E129

A petroleum-derived synthetic dye used to color thousands of American foods — and the most commonly used food coloring in the United States.

Why we flag it

Red 40 has been linked to behavioral effects in children, including hyperactivity and attention difficulties. A 2021 California state assessment of 25 studies concluded that synthetic food dyes — Red 40 in particular — can cause or worsen neurobehavioral problems in some kids, even at exposure levels considered safe by the FDA.

The dye also contains trace amounts of benzidine, a known human carcinogen, formed during manufacturing. The FDA permits these residues below a daily intake threshold; the European Food Safety Authority has set much stricter limits, and several European countries require a warning label on foods containing Red 40.

Where you'll find it

Anywhere bright red, pink, purple, or orange shows up in processed food. Common sources include:

What to look for instead

Many brands now use plant-based colorants that achieve similar shades without the synthetic dye:

On the label, look for the words "colored with fruit and vegetable juices," "no artificial colors," or specific natural colorants listed by name.